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Specialization

Lupus (SLE)

Diagnosis and long-term management of systemic lupus erythematosus and related autoimmune conditions.

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What is it?

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that can affect almost any organ in the body — skin, joints, kidneys, heart, lungs and nervous system. The immune system produces antibodies that attack the body's own tissues, causing inflammation and organ damage.

Main symptoms
  • "Butterfly rash" across the cheeks and nose (classic presentation)
  • Joint pain and swelling
  • Profound fatigue
  • Photosensitivity (heightened reaction to sunlight)
  • Hair loss
  • Mouth or nasal ulcers
  • Chest pain when breathing deeply
  • Proteinuria or other urinary changes (lupus nephritis)
How I treat it

Lupus treatment requires an individualized approach and continuous monitoring. Dr. Kaci coordinates interdisciplinary care focusing on flare control, organ protection and quality of life.

  • Hydroxychloroquine (Plaquenil) — cornerstone for all SLE patients
  • Corticosteroids during active flares
  • Immunosuppressants (Azathioprine, Mycophenolate Mofetil)
  • Belimumab and Anifrolumab (biologic therapies for lupus)
  • Sun protection and lifestyle modifications
  • Monitoring of kidneys, heart and nervous system
Frequently asked questions

Is lupus hereditary?

Lupus has a genetic component, but is not simply inherited. Environmental factors (sunlight, infections, stress) can trigger the disease in genetically predisposed individuals.

Can I have children if I have lupus?

Many women with lupus have successful pregnancies. However, careful planning with your rheumatologist and obstetrician is essential, as some medications must be stopped before conception.

How is lupus distinguished from other diseases?

Lupus is known as the "great imitator" because its symptoms resemble many other conditions. Diagnosis is made by combining symptoms, physical examination and specific laboratory tests such as ANA and anti-dsDNA.

Are flares predictable?

Often not completely, but many patients learn to recognise warning signs. Sunlight, infections, stress and medication changes are common triggers.

How long does treatment last?

Lupus is usually a lifelong condition, but many patients live well with proper management. Hydroxychloroquine is typically taken continuously as baseline protection.

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